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Employing automated workflows (Gluth et al., 2024, 2025) to screen various engineered and wildtype strains over time and in different conditions will provide a wealth of phenotypic data (i.e., growth, lipid production, etc.) that can be paired with proteomics (including PTMs), transcriptomics, metabolomics, and lipidomics data

Moreover, elucidations of epigenetic and gene regulatory mechanisms, such as lnc-HZ06, NCOA4, and IGF2BP3, provide much more profound insights into the ferroptosis-driven molecular pathways and their potential effects on RM

Levison BS, Zhang R, Wang Z, Fu X, DiDonato JA, Hazen SL

More than 40% of the patients are either homozygous for one SNP or compound heterozygous carriers